THE ROLE OF ADRENERGIC RECEPTORS IN THE ACTION OF ADRENALINE ON PLASMA LACTATE, GLUCOSE, LIVER, AND SKELETAL MUSCLE GLYCOGEN IN THE COMMON AFRICAN TOAD BUFO REGULARIS

In mammals, the roles of liver and skeletal muscle glycogen in adrenaline-induced hyperglycaemia are well known. However, amphibians, there is limited information on relative contribution hyperglycaemia. This study investigated effects adrenaline blood glucose, plasma lactate, liverand role adrenergic receptors common African toad, bufo regularis. One hundred twenty-five adult toads (70-100g) both sexes were randomly collected used study.Blood samples from truncus arteriosus to estimate glucose lactate levels. Blood was determined immediately by modified oxidase method. Plasma modification Barker-Summerson Liver gastrocnemius using anthrone reagents Adrenaline caused significant increase levels reduction glycogen. When pre-treated with propranolol or prazosin, adrenalines significantly reduced while prevented. Combination blockers abolished blocked produced adrenaline. The results this showed that adrenalinecaused breakdown, which resulted toad also alpha- beta-adrenergic involved mediating liver, glycogenolysis gluconeogenesis.